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January 19, 2023 1 min read

Minot and Murphy were two American physicians who, in the early 20th century, made a significant contribution to the treatment of anemia. They discovered that a diet rich in beef liver could be used to treat a specific type of anemia known as pernicious anemia.

Pernicious anemia is a type of anemia caused by a deficiency of vitamin B12. Minot and Murphy observed that patients with pernicious anemia who were given large amounts of beef liver as part of their diet showed improvement in their anemia. They found that beef liver was a rich source of vitamin B12, and that consuming large amounts of beef liver could help to alleviate the symptoms of pernicious anemia.

In 1926, Minot and Murphy published their findings in the Journal of the American Medical Association, describing the use of beef liver as a treatment for pernicious anemia. They showed that patients with pernicious anemia who were given a diet rich in liver showed significant improvement in their anemia, including an increase in red blood cells and hemoglobin levels.

Their discovery was a significant breakthrough in the treatment of pernicious anemia, as it provided a way to effectively treat the condition without the need for blood transfusions, which were the only treatment option at the time.

Minot and Murphy received the Nobel Prize in Physiology or Medicine in 1934 for their discovery of the treatment of pernicious anemia with liver. Their work laid the foundation for the use of vitamin B12 as a treatment for pernicious anemia and other B12 deficiencies.



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